Molecular Sieves
Apexbio Technology LLC TCS-PIM-1-4a 327033-36-3 50mg
TCS-PIM-1-4a is a small-molecule inhibitor targeting Pim kinases a family of serine/threonine kinases It is designed to selectively inhibit Pim kinases thereby modulating signaling pathways related to cell growth and survival TCS-PIM-1-4a exerts its biological activity primarily through activation of AMP-activated protein kinase (AMPK) resulting in inhibition of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway In cell-based studies TCS-PIM-1-4a demonstrates cytotoxic activity against diverse hematological tumor cell lines including myeloid and lymphoid subtypes with IC50 values ranging from approximately 0 8 to 40 M Based on these pharmacological properties TCS-PIM-1-4a holds research potential in investigations of Pim kinase signaling and therapeutic strategies for hematological malignancies
Medchemexpress LLC Avg-233 | 2151937-80-1 | 98.1% | 100 MG
AVG-233 is a potent, orally active RNA-dependent RNA polymerase (RdRp) inhibitor used for research into respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV strains and clinical isolates.
- Potent RNA-dependent RNA polymerase inhibitor.
- Reported EC50 = 0.14-0.31 μM against RSV strains and clinical isolates.
- Molecular formula: C26H22ClN5O3.
- Molecular weight: 487.94 g/mol.
- Available as a solid in multiple pack sizes (5 mg-500 mg).
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC SMI-4a (TCS-PIM-1-4a) | 438190-29-5 | 99.9% | 273.23 | 1 ML
SMI-4a (TCS-PIM-1-4a) is a potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 μM. It also inhibits Pim-2 (IC50 of 100 μM) but does not significantly inhibit other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity.
- Potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor.
- Inhibits Pim-2.
- Has anticancer activity.
Apexbio Technology LLC TCS-PIM-1-4a 327033-36-3 5mg
TCS-PIM-1-4a is a small-molecule inhibitor targeting Pim kinases a family of serine/threonine kinases It is designed to selectively inhibit Pim kinases thereby modulating signaling pathways related to cell growth and survival TCS-PIM-1-4a exerts its biological activity primarily through activation of AMP-activated protein kinase (AMPK) resulting in inhibition of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway In cell-based studies TCS-PIM-1-4a demonstrates cytotoxic activity against diverse hematological tumor cell lines including myeloid and lymphoid subtypes with IC50 values ranging from approximately 0 8 to 40 M Based on these pharmacological properties TCS-PIM-1-4a holds research potential in investigations of Pim kinase signaling and therapeutic strategies for hematological malignancies
Strem, An Ascensus Company CAS# 70955-01-0. 1kg. Molecular sieves, -600 mesh powder (Linde 4A). MFCD00131613
CAS# 70955-01-0. 1kg. Molecular sieves, -600 mesh powder (Linde 4A). MFCD00131613. Molecular Weight: . Molecular Formula: . Color/form: white pwdr. Strem# 93-5403. http://www.strem.com/catalog/v/93-5403/
Medchemexpress LLC Avg-233 | 2151937-80-1 | 98.1% | 25 MG
AVG-233 (CAS 2151937-80-1) is a small-molecule RNA-dependent RNA polymerase (RdRp) inhibitor used for research on respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV isolates (reported EC50 = 0.14-0.31 μM). Supplied as an off-white to yellow solid for laboratory use.
- Potent RdRp inhibitory activity (RSV EC50 = 0.14-0.31 μM).
- High purity solid, typically reported around 98%.
- Molecular formula C26H22ClN5O3; molecular weight 487.94.
- Available in multiple small-scale pack sizes suitable for research.
- Intended for in vitro and preclinical research; follow safety and storage recommendations.
Medchemexpress LLC Semaphorin-4A/SEMA4A 50ug
Recombinant mouse Semaphorin-4A extracellular domain expressed in HEK293 cells, supplied lyophilized with a C-terminal 6xHis tag. Provided at 50 μg with >95% purity and formulated for stability; certificate of analysis and datasheet are available for quality verification.
- Mouse extracellular domain (residues T33-H682).
- Expressed in HEK293 mammalian cells for proper folding and post-translational modifications.
- C-terminal 6xHis tag for affinity purification and detection.
- Lyophilized formulation with stabilizers for extended storage stability.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Supplied at 50 μg suitable for in vitro research applications.
- Certificate of analysis and datasheet provided for quality assurance.
Cayman Chemical 15-hydroxy Prostaglandin Dehydrogenase Polyclonal Antibody, 1 ea
Immunogen: Synthetic peptide from an internal region of human 15-PGDH • Host: Rabbit • Species Reactivity: (+) Human, baboon, mouse • Application: WB
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves 4 A bead5KG
Regeneration or ActivationA saturated molecular sieve can be restored to its original capacity by regeneration the principle of which involves changing the conditions surrounding the adsorbent to correspond to a very low equilibrium capacity. In general the greater the difference between the equilibrium capacities of adsorption and regeneration the more rapid and complete the regeneration.The sieve may be regenerated in one of four ways1. Thermal reactivation -The maximum regeneration temperature for Silica is 300C.2. Pressure reactivation3. Passing an appropriate fluid through the gel bed at normal temperature and pressure.4. Displacement of adsorbates by passing a high concentration of molecules in a fluid through the bed.
Selleck Chemical LLC Dyngo-4a
Dyngo-4a is a potent dynamin inhibitor with IC50 of 0 38 M 1 1 M and 2 3 M for DynI (brain) DynI (rec) and DynII (rec) respectively
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves 5 A 3.21KG
REAGENT Molecular sieves 5 A… 3.21KG
Medchemexpress LLC (Z)-1-((2-(trifluoromethyl)phenyl)methylene)-5-(thiazol-2-yl)thiourea | 438190-29-5 | MFCD01152003 | 99.9% | 273.23 g·mol⁻¹ | C11H6F3NO2S | 10 MG
SMI-4a is a selective, cell-permeable, ATP-competitive inhibitor of Pim-1 kinase supplied as a high-purity research chemical. It inhibits Pim-1 (IC50 = 24 μM; Ki = 0.6 μM) and Pim-2 (IC50 = 100 μM), is provided as a white to off-white solid in a 10 mg package, and includes recommended storage conditions for powder and solutions.
- Selective ATP-competitive Pim-1 kinase inhibitor suitable for research use.
- High purity suitable for biochemical and cellular assays.
- Supplied as a 10 mg solid for small-scale experiments.
- Includes storage recommendations for powder and dissolved samples.
- Contains chemical identifiers for unambiguous compound tracking.
Chem-Impex International, Inc. Molecular sieves, 3?, beads 8-12 mesh | 1318-02-1 | MFCD00147627 | 1KG
Molecular sieves, 3?, beads 8-12 mesh, 1318-02-1, MFCD00147627, 1KG
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves, 4 Ã… pellets, 1.6 mm diameter | 70955-01-0 | MFCD00131613 | 1KG
Molecular sieves, 4 Ã… pellets, 1.6 mm diameter | 70955-01-0 | MFCD00131613 | 1KG
Cayman Chemical 15hydroxy ProstaglndIn Dehy
Source: Active recombinant human C-terminal His-tagged 15-PGDH expressed in E. coli • Amino acids: 3-256 • MW: 29.9 kDa