Molecular sieves are materials with pores of uniform size and diameter that are similar in size to small molecules; used to separate molecules by size; available in various pore size ranges, with drying solvent indicators, etc.
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Nutlin-3a ((-)-Nutlin-3) the active enantiomer of Nutlin-3 inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner
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SMI-4a (TCS PIM-1 4a) is a potent inhibitor of Pim1 with IC50 of 17 nM modestly potent to Pim-2 does not significantly inhibit any other serine/threonine- or tyrosine-kinases
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